Dexamethasone Hydrochloride CAS 69351-57-1
| CAS No. | 69351-57-1 |
| Molecular Formula | C22H29FO5 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Dexamethasone Hydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Dexamethasone Hydrochloride (CAS 69351-57-1) is a high-purity analytical reference standard with the molecular formula C22H29FO5HCl and a molecular weight of 428.92 g/mol.
The molecular framework of Dexamethasone Hydrochloride (C22H29FO5HCl) is characterized by a flavonoid core, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C22H29FO5 HCl |
| Molecular Weight | 428.92 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | F/Cl-containing |
Related Dexamethasone Standards
- Dexamethasone EP Impurity H (CAS 10106-41-9)
- Dexamethasone Impurity 116 (CAS 107419-73-8)
- Dexamethasone EP Impurity G (CAS 1177-87-3)
- Dexamethasone impurity 63 (CAS 1202001-99-7)
- Dexamethasone impurity 65 (CAS 1202002-01-4)
- Dexamethasone EP Impurity E (CAS 13209-41-1)
- Dexamethasone Impurity 112 (CAS 134429-26-8)
- Dexamethasone impurity 90 (CAS 134429-31-5)
Recommended Standards
- (S)-2-Amino-6-(benzyloxy)-6-oxohexanoic acid hydrochloride (CAS 1956434-60-8)
- Dibenzo[b,d]selenophene 5-oxide (CAS 30467-70-0)
- 4-(4-Hydroxyphenyl)pyrrolidine-3-carboxylic acid hydrochloride (CAS 1808717-05-6)
- Ethyl 2-((7-methyl-2-phenylimidazo[1,2-a]pyrimidin-5-yl)oxy)acetate (CAS 866043-19-8)
- 5-((1H-Imidazol-4-yl)methyl)-2,4-diethylthiazole (CAS 687995-60-4)
- Ethyl 4-(benzyloxy)-2,3-difluorobenzoate (CAS 1879026-11-5)
- <I>N</I>-Fmoc-piperidine-2-carboxylic acid (CAS 105751-19-7)
- 2-(1-Phenyl-1H-imidazol-2-yl)acetonitrile (CAS 63928-10-9)
- Thalrugosaminine (CAS 22226-73-9)
- Copper Peptide ยท2 acetate salt (CAS 130120-57-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com