rac-Levothyroxine EP Impurity J (3,3'-DL-Diiodothyronine) CAS 70-40-6

Purity 97%+In StockPharmaceutical Standards
CAS No.70-40-6
Molecular FormulaC15H13I2NO4
Molecular Weight525.08 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

rac-Levothyroxine EP Impurity J (3,3'-DL-Diiodothyronine) CAS 70-40-6 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 525.08 g/mol gives rac-Levothyroxine EP Impurity J (3,3'-DL-Diiodothyronine) distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

rac-Levothyroxine EP Impurity J (3,3'-DL-Diiodothyronine) (CAS 70-40-6), molecular formula C15H13I2NO4 and molecular weight 525.08 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, rac-Levothyroxine EP Impurity J (3,3'-DL-Diiodothyronine) (C15H13I2NO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 525.08 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC15H13I2NO4
Molecular Weight525.08 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Halogen ContentI-containing
Nitrogen Atoms1

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