Ponatinib CAS 943319-70-8
| CAS No. | 943319-70-8 |
| Molecular Formula | C29H27F3N6O |
| Molecular Weight | 532.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Ponatinib (C29H27F3N6O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Ponatinib (CAS 943319-70-8), molecular formula C29H27F3N6O and molecular weight 532.56 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Ponatinib meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C29H27F3N6O |
| Molecular Weight | 532.56 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 6 |
Related Ponatinib Standards
- Ponatinib Impurity 15 (E-Isomer) (CAS CATO-C4X-226915)
- Ponatinib Impurity 18 (Z-Isomer) (CAS CATO-C4X-226918)
- Ponatinib Impurity 43 (E-Isomer) (CAS CATO-C4X-226943)
- Ponatinib Impurity 44 (Z-Isomer) (CAS CATO-C4X-226944)
- Ponatinib-d8 (CAS 1562993-37-6)
- Ponatinib Impurity 11 (CAS CATO-C4X-226911)
- Ponatinib Active Metabolite AP24567(M42) (CAS 943319-87-7)
- Ponatinib Impurity 54 (CAS CATO-C4X-226954)
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Why CATO?
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