Ponatinib Impurity 11 CAS CATO-C4X-226911
| CAS No. | CATO-C4X-226911 |
| Molecular Formula | C26H32F6N6 |
| Molecular Weight | 542.56 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Ponatinib Impurity 11 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Ponatinib Impurity 11 (CAS CATO-C4X-226911) is a certified pharmaceutical impurity reference standard with the molecular formula C26H32F6N6 and a molecular weight of 542.56 g/mol.
The molecular framework of Ponatinib Impurity 11 (C26H32F6N6) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C26H32F6N6 |
| Molecular Weight | 542.56 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 6 |
Related Ponatinib Standards
- Ponatinib-d8 (CAS 1562993-37-6)
- Ponatinib Impurity 10 (CAS CATO-C4X-226910)
- Ponatinib impurity 6 (CAS 2227480-51-3)
- Ponatinib (CAS 943319-70-8)
- Ponatinib Impurity 15 (E-Isomer) (CAS CATO-C4X-226915)
- Ponatinib Impurity 18 (Z-Isomer) (CAS CATO-C4X-226918)
- Ponatinib Impurity 43 (E-Isomer) (CAS CATO-C4X-226943)
- Ponatinib Impurity 44 (Z-Isomer) (CAS CATO-C4X-226944)
Recommended Standards
- 1,3-Bis-(1-benzyl-4-trifluoromethyl-piperidin-4-yl)-urea (CAS 2097068-72-7)
- Eravacycline Impurity 4(TP-4308） (CAS CATO-C4X-29384)
- Nilotinib Impurity 43 (CAS CATO-C4X-125643)
- Eravacycline Impurity 5(TP-6773） (CAS CATO-C4X-29385)
- Cabozantinib Impurity 41 (CAS 2105956-20-3)
- Azathioprine Impurity 14 (CAS 49808-20-0)
- Revefenacin impurity 95 (CAS CATO-C4X-203195)
- (R)-3-Cyclopentylmorpholine (CAS 1270034-44-0)
- 3-(3,5-Difluorophenoxy)aniline (CAS 887580-88-3)
- Calcitriol Impurity 58 (CAS CATO-C4X-151058)
- 2-Bromo-4-(difluoromethyl)-5-methoxypyridine-3-sulfonamide (CAS 1805351-94-3)
- 1-((Tetrahydro-2H-pyran-2-yl)methyl)piperazine (CAS 130288-92-5)
- Methyl 2-(2-methyl-4-(6-methylpyridin-2-yl)phenyl)acetate (CAS 1648864-46-3)
- Semaglutide impurity 258 (CAS CATO-C4X-2226258)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com