Clofazimine Impurity 9 CAS 96762-04-8
| CAS No. | 96762-04-8 |
| Molecular Formula | C24H16Cl2N4 |
| Molecular Weight | 431.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Clofazimine Impurity 9 (C24H16Cl2N4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Clofazimine Impurity 9 (CAS 96762-04-8, C24H16Cl2N4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Clofazimine Impurity 9 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H16Cl2N4 |
| Molecular Weight | 431.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ＞95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Clofazimine Standards
- Clofazimine Impurity 26 (CAS CATO-C4X-207126)
- Clofazimine Impurity 28 (CAS CATO-C4X-207128)
- Clofazimine Impurity 29 (CAS CATO-C4X-207129)
- Clofazimine EP Impurity A (CAS 102262-55-5)
- Clofazimine Impurity 3 (CAS 90712-89-3)
- Clofazimine Impurity 14 (CAS CATO-C4X-207114)
- Clofazimine Impurity 17 (CAS CATO-C4X-207117)
- Clofazimine Impurity 2 (CAS 2158184-11-1)
Recommended Standards
- (((5-(5-Oxo-4,5-dihydroisoxazol-3-yl)furan-2-yl)phosphoryl)bis(oxy))bis(methylene) bis(2-methylpropanoate) (CAS 1243184-62-4)
- Tert-butyl 4-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamoyl)piperazine-1-carboxylate (CAS 1704068-57-4)
- Tert-butyl 4-((3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamoyl)piperazine-1-carboxylate (CAS 1704081-91-3)
- 1-Benzyl 2-methyl (2S,3R)-3-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propyl)pyrrolidine-1,2-dicarboxylate (CAS 2376704-00-4)
- Norepinephrine Impurity 21 (CAS 490-89-1)
- Pitavastatin Impurity 89 (CAS CATO-C4X-103789)
- Ibrutinib Impurity 183 (CAS CATO-C4X-1064183)
- 5-Bromo-2-chloro-n-ethyl-nicotinamide (CAS 1249312-18-2)
- 8-bromo-2,3-dihydro-1,4-benzoxazepin-5-amine (CAS 1628256-49-4)
- 1-(2-Fluoro-5-iodophenyl)ethan-1-one (CAS 1159512-66-9)
- 4'-Heptyl-3-methyl-[1,1'-biphenyl]-4-carboxylic acid (CAS 920269-91-6)
- 5-(n-Cyclohexylsulfamoyl)thiophene-3-carboxylic acid (CAS 1036571-81-9)
- 148252-45-3 2-bromo-9-chloro-1-nonene DTXSID20435714 (CAS 148252-45-3)
- Peptide 74 (H-8545.0500) (CAS 132116-39-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com