Clofazimine Impurity 29 CAS CATO-C4X-207129
| CAS No. | CATO-C4X-207129 |
| Molecular Formula | C24H16Cl2N4 |
| Molecular Weight | 431.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 431.32 g/mol gives Clofazimine Impurity 29 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Clofazimine Impurity 29 (CAS CATO-C4X-207129, C24H16Cl2N4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Clofazimine Impurity 29 (C24H16Cl2N4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 18.0, corresponding to approximately 18 ring(s) or double-bond equivalent(s). With a molecular weight of 431.32 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Clofazimine Impurity 29 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H16Cl2N4 |
| Molecular Weight | 431.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Clofazimine Standards
- Clofazimine Impurity 26 (CAS CATO-C4X-207126)
- Clofazimine Impurity 28 (CAS CATO-C4X-207128)
- Clofazimine EP Impurity A (CAS 102262-55-5)
- Clofazimine Impurity 9 (CAS 96762-04-8)
- Clofazimine Impurity 3 (CAS 90712-89-3)
- Clofazimine Impurity 14 (CAS CATO-C4X-207114)
- Clofazimine Impurity 17 (CAS CATO-C4X-207117)
- Clofazimine Impurity 2 (CAS 2158184-11-1)
Recommended Standards
- Tofacitinib Impurity 211 (CAS CATO-C4X-1079211)
- (((5-(5-Oxo-4,5-dihydroisoxazol-3-yl)furan-2-yl)phosphoryl)bis(oxy))bis(methylene) bis(2-methylpropanoate) (CAS 1243184-62-4)
- 4-Chloro-5-(4-(3-chlorophenyl)piperazin-1-yl)-2-(4-methoxyphenyl)pyridazin-3(2H)-one (CAS 477867-46-2)
- Tert-butyl 4-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamoyl)piperazine-1-carboxylate (CAS 1704068-57-4)
- Relugolix Impurity 172 (CAS CATO-C4X-2429172)
- Vortioxetine Impurity 136 (CAS CATO-C4X-1056136)
- Progesterone Impurity 79 (CAS CATO-C4X-150279)
- Calcium Dobesilate Impurity 15 (CAS 35857-70-6(free base))
- 2-(9,9-Dibutyl-9H-fluoren-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 785051-52-7)
- Sodium 2,5-dichlorobenzenesulfinate (CAS 38945-00-5)
- 5-(2,3-Dihydro-1h-inden-5-yl)-5-methylimidazolidine-2,4-dione (CAS 956411-90-8)
- Potassium (E)-4-(2-(thiophen-2-yl)vinyl)pyrimidine-2-thiolate (CAS 318248-61-2)
- (3-Methyl-4,5-dihydro-1,2-oxazol-5-yl)methanamine hydrochloride (CAS 1185301-13-6)
- Des-Trp25-Tirzepatide (CAS CATO-CPTD788948)
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