Clofazimine Impurity 17 CAS CATO-C4X-207117
| CAS No. | CATO-C4X-207117 |
| Molecular Formula | C24H20Cl2N4 |
| Molecular Weight | 435.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Clofazimine Impurity 17 (C24H20Cl2N4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a process- or degradation-related impurity, Clofazimine Impurity 17 (CAS CATO-C4X-207117, C24H20Cl2N4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Clofazimine Impurity 17 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H20Cl2N4 |
| Molecular Weight | 435.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Clofazimine Standards
- Clofazimine Impurity 14 (CAS CATO-C4X-207114)
- Clofazimine Impurity 3 (CAS 90712-89-3)
- Clofazimine Impurity 2 (CAS 2158184-11-1)
- Clofazimine Impurity 26 (CAS CATO-C4X-207126)
- Clofazimine Impurity 28 (CAS CATO-C4X-207128)
- Clofazimine Impurity 29 (CAS CATO-C4X-207129)
- Clofazimine EP Impurity A (CAS 102262-55-5)
- Clofazimine Impurity 9 (CAS 96762-04-8)
Recommended Standards
- 3-[[4-Bromo-3-(1,3-dioxolan-2-yl)phenyl]methyl]-2-butyl-1,3-diazaspiro[4.4]non-1-en-4-one (CAS 254744-55-3)
- (5-Bromopyridin-3-yl)(4-(4-(thiophen-3-yl)thiazol-2-yl)piperazin-1-yl)methanone (CAS 1448075-21-5)
- (S)-2-Amino-3-(5-(bis(2-chloroethyl)amino)-1-(p-tolyl)-1H-benzo[d]imidazol-2-yl)propanoic acid (CAS 72437-91-3)
- 1-{[3,5-bis(trifluoromethyl)phenyl]methyl}-N-[2-(dimethylamino)ethyl]-2-oxo-1,2-dihydropyridine-3-carboxamide (CAS 338782-07-3)
- Atosiban Impurity 21 (CAS CATO-C4X-229321)
- CAS 879973-83-8 (CAS 879973-83-8)
- Empagliflozin impurity 318 (CAS CATO-C4X-1065318)
- 3-bromopropyl 3,4-dimethylphenyl ether (CAS 103857-79-0)
- 4-Chlorophenyl 4-fluoropyridin-2-ylcarbamate (CAS 1993323-78-6)
- C-[5-(5-TRifluoromethyl-pyridin-2-yl)-[1,2,4]oxadiazol-3-yl]-methylamine hydrochloride (CAS 2108262-95-7)
- N-(2-(ethylamino)cyclohexyl)acetamide (CAS 1353952-92-7)
- Nintedanib Impurity 2 (CAS 2410284-90-9)
- 2-(4-Amino-2-chlorophenoxy)-n,n-diethylacetamide (CAS 954571-02-9)
- 81988-89-8 UH11FDQ454 Ramoplanin A(sub 3) Ramoplanin A3 (S)-2-(3-Chloro-4-hydroxyphenyl)-N-(N(sup 2)-((2Z,4Z)-8-methyl-2,4-nonadienoyl)-(S)-asparaginyl-(2S,3S)-3-hydroxyasparaginyl-(R)-2-(p-hydroxyphenyl)glycyl-(R)-ornithyl-(2R,3R)-allothreonyl-2-(p-hydroxyphenyl)glycyl-2-(p-hydroxyphenyl)glycyl-(2S,3S)-allothreonyl-(S)-phenylalanyl-(R)-ornithyl-(S)-2-(p-((2-O-alpha-D-mannopyranosyl-alpha-D-mannopyranosyl)oxy)phenyl)glycyl-(2R,3R)-allothreonyl-(S)-2-(p-hydroxyphenyl)glycylglycyl-(S)-leucyl-(R)-alanyl)glycine psi1-lactone Ramoplanin A 1 (peptide moiety), 1-(N(sup 2)-methyl-1-oxo-2,4-nonadienyl)-L-asparagine)-11-(L-2-(4-((2-O-alpha-D-mannopyranosyl-alpha-D-mannopyranosyl)oxy)phenyl)glycine)-, (Z,Z)- UNII-UH11FDQ454 (CAS 81988-89-8)
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