Diclofenac sodium impurity 66 CAS CATO-C4X-105166
| CAS No. | CATO-C4X-105166 |
| Molecular Formula | C15H12Cl2NO2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 332.16 g/mol gives Diclofenac sodium impurity 66 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Diclofenac sodium impurity 66 (CAS CATO-C4X-105166) is a certified pharmaceutical impurity reference standard with the molecular formula C15H12Cl2NO2Na and a molecular weight of 332.16 g/mol.
Diclofenac sodium impurity 66 (C15H12Cl2NO2Na) contains a salt form, a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Diclofenac sodium impurity 66 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H12Cl2NO2 Na |
| Molecular Weight | 332.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Diclofenac Standards
- Diclofenac Impurity 21 (CAS 105836-68-8)
- Diclofenac Impurity 8 (CAS 106610-60-0)
- Diclofenac Epolamine (CAS 119623-66-4)
- Diclofenac Impurity 60 (CAS 120339-20-0)
- Diclofenac Impurity 19 (CAS 1205-40-9)
- Diclofenac Impurity 31 (CAS 1219112-85-2)
- Diclofenac Sodium Impurity 34 (CAS 123790-84-1)
- Diclofenac impurity f (CAS 124426-56-8)
Recommended Standards
- Ibuprofen Impurity 35 (CAS 103775-30-6)
- Ibrutinib Impurity 9 (CAS CATO-C4X-10649)
- Nicergoline EP Impurity E (CAS 57935-66-7)
- 5-(Difluoromethoxy)-1H-indazole (CAS 105391-65-9)
- 5-(pyrrolidin-1-ylmethyl)thiophene-2-carboxylic acid,HCl (CAS 1431966-78-7)
- (2,2-Dimethyl-3,4-dihydro-2H-1-benzopyran-6-yl)methanol (CAS 61370-82-9)
- 2,2-dimethyloctan-3-amine (CAS 1099683-24-5)
- 1-(2-Cyclopropyl-6-(4-fluorophenyl)pyrimidin-4-yl)-1,4-diazepane (CAS 1707566-52-6)
- 2-(1-(4-Methoxyphenyl)ethylidene)hydrazine-1-carboxamide (CAS 717-14-6)
- SAMS Peptide (CAS 125911-68-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com