Ibrutinib Impurity 34 CAS CATO-C4X-106434
| CAS No. | CATO-C4X-106434 |
| Molecular Formula | C19H17N5O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ibrutinib Impurity 34.
As a process- or degradation-related impurity, Ibrutinib Impurity 34 (CAS CATO-C4X-106434, C19H17N5O2CH4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Ibrutinib Impurity 34 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 363.42 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Ibrutinib Impurity 34 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H17N5O2 CH4 |
| Molecular Weight | 363.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Ibrutinib Standards
- Ibrutinib Impurity 47 (CAS 1022150-11-3)
- Ibrutinib Impurity 10 (CAS 1022150-12-4)
- Ibrutinib Impurity 80 (CAS 109384-19-2)
- Ibrutinib Impurity 53 (CAS 109831-68-7)
- Ibrutinib Impurity 54 (CAS 1260862-85-8)
- Ibrutinib Impurity 4 (CAS 1288338-95-3)
- Ibrutinib Impurity 3 (CAS 1288338-96-4)
- Ibrutinib Impurity 81 (CAS 143667-36-1)
Recommended Standards
- Prasugrel EP Impurity E (CAS 1056459-37-0)
- Cinepazide Impurity 6 (CAS 20266-00-6)
- Ceftazidime impurity 115 (CAS CATO-C4X-1212115)
- 2-amino-2-(3-chlorophenyl)propanamide (CAS 1183329-49-8)
- (2R)-3,4-Dibromopyrrolidine-2-carboxylic butyric anhydride (CAS 64229-39-6)
- Sar-R-G-D-S-P (CAS 133525-11-8)
- 3-Methoxyisoquinolin-8-amine (CAS 1374652-26-2)
- 4-(4-Chlorobenzyl)tetrahydro-2h-pyran-4-amine hydrochloride (CAS 1439902-83-6)
- 3-Bromo-5-methoxy-1-methyl-1H-1,2,4-triazole (CAS 1306739-06-9)
- Exenatide Acetate (CAS 141732-76-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com