Ibrutinib Impurity 69 CAS CATO-C4X-106469
| CAS No. | CATO-C4X-106469 |
| Molecular Formula | C36H27B3O6 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Ibrutinib Impurity 69 (CAS CATO-C4X-106469), a pharmacopoeial impurity reference standard (molecular formula C36H27B3O6C12H11BO3, MW 802.06 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Ibrutinib Impurity 69 (C36H27B3O6C12H11BO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 30.0, corresponding to approximately 30 ring(s) or double-bond equivalent(s). With a molecular weight of 802.06 g/mol, it falls into the high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C36H27B3O6 C12H11BO3 |
| Molecular Weight | 802.06 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 30.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Ibrutinib Standards
- Ibrutinib Impurity 47 (CAS 1022150-11-3)
- Ibrutinib Impurity 10 (CAS 1022150-12-4)
- Ibrutinib Impurity 80 (CAS 109384-19-2)
- Ibrutinib Impurity 53 (CAS 109831-68-7)
- Ibrutinib Impurity 54 (CAS 1260862-85-8)
- Ibrutinib Impurity 4 (CAS 1288338-95-3)
- Ibrutinib Impurity 3 (CAS 1288338-96-4)
- Ibrutinib Impurity 81 (CAS 143667-36-1)
Recommended Standards
- (1S,2S,3R,4R)-Peramivir Impurity 95 (CAS 229615-05-8)
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- Capivasertib Impurity 35 (CAS CATO-C4X-331235)
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Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com