Empagliflozin impurity 185 CAS CATO-C4X-1065185

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-1065185
Molecular FormulaC13H7BrFIO
Molecular Weight405.00 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Empagliflozin impurity 185 CAS CATO-C4X-1065185 chemical structure

Description

Empagliflozin impurity 185 (CAS CATO-C4X-1065185) is a certified pharmaceutical impurity reference standard with the molecular formula C13H7BrFIO and a molecular weight of 405.00 g/mol.

The molecular framework of Empagliflozin impurity 185 (C13H7BrFIO) is characterized by a hydroxyl group, an ether linkage, fluorine/bromine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Empagliflozin impurity 185 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC13H7BrFIO
Molecular Weight405.00 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity>95%
StorageStore at room temperature, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentF/Br/I-containing

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