Empagliflozin Impurity 311 CAS CATO-C4X-1065311
| CAS No. | CATO-C4X-1065311 |
| Molecular Formula | C18H18ClIO2 |
| Molecular Weight | 428.69 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Empagliflozin Impurity 311 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Empagliflozin Impurity 311 (CAS CATO-C4X-1065311, C18H18ClIO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Empagliflozin Impurity 311 (C18H18ClIO2) contains a steroid core, a hydroxyl group, an ether linkage, chlorine/iodine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C18H18ClIO2 |
| Molecular Weight | 428.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl/I-containing |
Related Empagliflozin Standards
- Empagliflozin impurity 266 (CAS CATO-C4X-1065266)
- Empagliflozin impurity 267 (CAS CATO-C4X-1065267)
- Empagliflozin impurity 268 (CAS CATO-C4X-1065268)
- Empagliflozin impurity 269 (CAS CATO-C4X-1065269)
- Empagliflozin Impurity 289 (CAS CATO-C4X-1065289)
- Empagliflozin Impurity 290 (CAS CATO-C4X-1065290)
- Empagliflozin Impurity 291 (CAS CATO-C4X-1065291)
- Empagliflozin Impurity 312 (CAS CATO-C4X-1065312)
Recommended Standards
- Tocopherol Impurity 4 (CAS 3808-26-2)
- Cholesterol For Parenteral Use EP Impurity F (CAS 604-35-3)
- Cholesterol Impurity 39 (CAS 17137-70-1)
- 2,4-Dichlorophenyl 2-(4-chlorophenyl)quinoline-4-carboxylate (CAS 355433-68-0)
- Vortioxetine Impurity 51 (CAS 1610527-49-5)
- Rosuvastatin Impurity 229 (CAS CATO-C4X-1169229)
- Trimetazidine EP Impurity F（Dihydrochloride） (CAS 113698-83-2)
- 3-(4-Chloro-6-methylpyridin-2-yl)propan-1-amine (CAS 1393581-96-8)
- 1-(5-Chloro-2-fluorobenzyl)piperazine (CAS 1251127-61-3)
- Bilastine impurity 59 (CAS CATO-C4X-225359)
- 2-(Methyl(1-(thiazol-2-yl)ethyl)amino)ethanol (CAS 1353979-09-5)
- Akti-1/2 (CAS 612847-09-3)
- 6-(Ethoxycarbonyl)picolinic acid (CAS 21855-16-3)
- Tirzepatide-d7 Ditrifluoroacetate (CAS CATO-CPTD788698)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com