Amlodipine Impurity 17 CAS CATO-C4X-109517
| CAS No. | CATO-C4X-109517 |
| Molecular Formula | C21H19ClN2O7 |
| Molecular Weight | 446.84 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Amlodipine Impurity 17 (C21H19ClN2O7) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Amlodipine Impurity 17 (CAS CATO-C4X-109517) is a certified pharmaceutical impurity reference standard with the molecular formula C21H19ClN2O7 and a molecular weight of 446.84 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Amlodipine Impurity 17 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H19ClN2O7 |
| Molecular Weight | 446.84 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Amlodipine Standards
- Amlodipine Impurity 20 (CAS 400024-08-0)
- Amlodipine Impurity 84 (CAS 906098-03-1)
- Amlodipine Impurity 117 (CAS CATO-C4X-1095117)
- Amlodipine Impurity 133 (CAS CATO-C4X-1095133)
- Amlodipine Impurity 82 (CAS CATO-C4X-109582)
- Amlodipine Impurity 42 (CAS 158151-92-9)
- Amlodipine Impurity 43 (CAS CATO-C4X-109543)
- Amlodipine Impurity 51 (CAS 93848-81-8)
Recommended Standards
- 3,3'-((2-Chlorophenyl)methylene)bis(4-hydroxy-2h-chromen-2-one) (CAS 4322-58-1)
- Demeclocycline EP Impurity F (CAS CATO-C4X-16086)
- 2-(3-Nitrophenyl)-2-oxoethyl 6-chloro-2-phenylquinoline-4-carboxylate (CAS 355420-42-7)
- Demeclocycline EP Impurity G (CAS 22688-73-9)
- Daprodustat Impurity 29 (CAS CATO-C4X-240729)
- Indapamide EP Impurity B (CAS 63968-75-2)
- Glimepiride Impurity 25 (CAS CATO-C4X-110225)
- N-(4-(Dimethylamino)benzylidene)thiophene-2-sulfonamide (CAS 308293-20-1)
- 2-(4-(Bromomethyl)phenoxy)-5-(trifluoromethyl)pyridine (CAS 1160430-95-4)
- 2-(Methylthio)-[1,1'-biphenyl]-3-carboxylic acid (CAS 168618-43-7)
- Curcumol (CAS 4871-97-0)
- 3-Chloro-4'-(pyrrolidin-1-ylsulfonyl)-[1,1'-biphenyl]-4-ol (CAS 1262002-21-0)
- 3-(2-Aminoethyl)-5-bromo-6-fluoroindolin-2-one (CAS 1275351-43-3)
- Peptide Impurity 81 TFA (CAS CATO-CPTD788581)
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