Palbociclib Impurity 63 CAS CATO-C4X-112563
| CAS No. | CATO-C4X-112563 |
| Molecular Formula | C19H24ClN3O2 |
| Molecular Weight | 361.87 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Palbociclib Impurity 63 (CAS CATO-C4X-112563) is a certified pharmaceutical impurity reference standard with the molecular formula C19H24ClN3O2 and a molecular weight of 361.87 g/mol.
Palbociclib Impurity 63 (C19H24ClN3O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H24ClN3O2 |
| Molecular Weight | 361.87 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Palbociclib Standards
- Palbociclib Impurity 158 (CAS 2639903-34-5)
- Palbociclib Impurity 166 (CAS CATO-C4X-1125166)
- Palbociclib Impurity 155 (CAS CATO-C4X-1125155)
- Palbociclib impurity 161 (CAS CATO-C4X-1125161)
- Palbociclib Impurity 192 (CAS CATO-C4X-1125192)
- Palbociclib Impurity 86 (CAS 2363172-64-7)
- Palbociclib Impurity 25 (CAS 1016636-76-2)
- Palbociclib Impurity 114 (CAS 412348-27-7)
Recommended Standards
- 299935-27-6 5-(4-Chlorophenyl)-2-{[(2-piperazin-1-ylethyl)amino]methylene}cyclohexane-1,3-dione MFCD01957386 (CAS 299935-27-6)
- Dasatinib Impurity 74 (CAS CATO-C4X-160774)
- Sigma-1 receptor precursor (CAS 2448691-41-4)
- 1,4-Dibromo-2,3-difluoro-5,6-dinitrobenzene (CAS 1283598-32-2)
- Gemcitabine Impurity 37 (CAS 122111-08-4)
- Epothilone B (CAS 152044-54-7)
- Oclacitinib Impurity 15 (CAS 2585670-75-1)
- Sildenafil Impurity 7 (CAS 139756-22-2)
- (1-Acetamido-2-phenylethyl)boronic acid (CAS 88765-81-5)
- (R,E)-3,7-Dimethyloct-2-enedioic acid (CAS 87172-91-6)
- 5-(Chloromethyl)-2-(2-fluoro-4-(trifluoromethyl)phenyl)-4-methylthiazole (CAS 317319-37-2)
- D-Lysine dihydrochloride (CAS 10303-72-7)
- 4-Chloro-3-methoxyphenylacetic Acid (CAS 13726-19-7)
- Brain Injury Derived Neurotrophic Peptide (H-3914.0001) (CAS 148330-12-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com