Aprepitant impurity 57 Dimethyl ammonium salt CAS CATO-C4X-114157
| CAS No. | CATO-C4X-114157 |
| Molecular Formula | C23H22F7N4O6P |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Aprepitant impurity 57 Dimethyl ammonium salt (CAS CATO-C4X-114157) is a certified pharmaceutical impurity reference standard with the molecular formula C23H22F7N4O6PC7H17NO5 and a molecular weight of 809.63 g/mol.
Structurally, Aprepitant impurity 57 Dimethyl ammonium salt (C23H22F7N4O6PC7H17NO5) contains a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.5, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 809.63 g/mol, it falls into the high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C23H22F7N4O6P 2*C7H17NO5 |
| Molecular Weight | 809.63 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related Aprepitant Standards
- Aprepitant D4 (CAS 1133387-60-6)
- Aprepitant USP Related Compound A (CAS 1148113-53-4)
- Aprepitant Impurity 2 (CAS 1185502-97-9)
- Aprepitant-13C2,d2 (Major) (CAS 1217676-37-3)
- Aprepitant Impurity 7 (CAS 1242175-34-3)
- Aprepitant Impurity 5 (CAS 1242175-40-1)
- Aprepitant Impurity 33 (CAS 1265177-56-7)
- Aprepitant Impurity 38 (CAS 127852-28-2)
Recommended Standards
- Bosentan Impurity 02 (CAS 301646-61-7)
- Selexipag Impurity 36 (CAS CATO-C4X-196136)
- Atogepant Impurity 53 (CAS 1456803-44-3)
- 2-(2,4-Difluorobenzoyl)oxazole (CAS 898760-38-8)
- 3-(Piperidin-1-yl)quinazolin-4(3H)-one (CAS 89804-94-4)
- 5-((1H-Imidazol-4-yl)methyl)-3-propylimidazolidine-2,4-dione (CAS 804435-18-5)
- 2-chloro-N-[4-(morpholin-4-ylmethyl)phenyl]propanamide hydrochloride (CAS 1803566-26-8)
- 4-((4,6-Dimethoxypyrimidin-5-yl)sulfonyl)thiomorpholine (CAS 861208-71-1)
- 1-(6-Methyl-2,3-dihydro-1H-pyrrolizin-5-yl)propan-1-one (CAS 97073-08-0)
- Tau Peptide (512-525) amide trifluoroacetate salt (CAS 2022956-61-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com