Dexamethasone Impurity 43 CAS CATO-C4X-116543
| CAS No. | CATO-C4X-116543 |
| Molecular Formula | C22H29FO4 |
| Molecular Weight | 376.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Dexamethasone Impurity 43.
CATO supplies Dexamethasone Impurity 43 (CAS CATO-C4X-116543), a pharmacopoeial impurity reference standard (molecular formula C22H29FO4, MW 376.46 g/mol) used for the identification and quantification of trace impurities in APIs.
Dexamethasone Impurity 43 (C22H29FO4) contains a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Dexamethasone Impurity 43 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H29FO4 |
| Molecular Weight | 376.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Dexamethasone Standards
- Dexamethasone Isonicotinate EP Impurity C (CAS 426-15-3)
- Dexamethasone EP Impurity F (CAS 382-67-2)
- Dexamethasone sodium phosphate EP Impurity G (CAS 37927-01-8)
- Dexamethasone Desfluoro 11-Epimer (CAS 78761-59-8)
- Dexamethasone Oxetanone (CAS 4089-36-5)
- Dexamethasone Impurity 104 (CAS 62800-49-1)
- Dexamethasone Impurity 120 (CAS CATO-C4X-1165120)
- Dexamethasone Impurity 23 (CAS 59860-99-0)
Recommended Standards
- 2-[(5-amino-1,3,4-thiadiazol-2-yl)sulfanyl]-N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1h-pyrazol-4-yl)acetamide (CAS 329921-17-7)
- (11α,16α,17β)Androsta-1,4-diene-17-carboxylic acid, 9-fluoro-11-hydroxy-16-methyl-3-oxo-methyl EsterDISCONTINUED. Please see A653305 (CAS 85617-70-5)
- 5F-MDMB-PICA (CAS 1971007-88-1)
- Betamethasone Impurity 125 (CAS CATO-C4X-1437125)
- Allisartan Isoproxil Impurity 24 (CAS CATO-C4X-321724)
- Retigabine Impurity 3 (CAS 1263404-73-4)
- Progesterone Impurity 34 (CAS 60966-36-1)
- 5-Bromo-2,3,4-trifluoropyridine (CAS 1805468-64-7)
- 2-Cyanoethyl ether (CAS 1656-48-0)
- N-(2-Cyano-3-methylbutan-2-yl)-2-((5,6-di-p-tolyl-1,2,4-triazin-3-yl)thio)acetamide (CAS 757214-05-4)
- (3-Amino-1-benzylpyrrolidin-3-yl)methanol (CAS 475469-13-7)
- 4-(4-(2-Fluorobenzyl)-5-methyl-4H-1,2,4-triazol-3-yl)-1-methyl-1H-pyrazol-5-amine (CAS 955966-43-5)
- 288401-62-7 4-fluoranyl-6-(2H-1,2-oxazol-5-ylidene)cyclohexa-2,4-dien-1-one 4-fluoro-6-(2H-isoxazol-5-ylidene)-1-cyclohexa-2,4-dienone A819628 (CAS 288401-62-7)
- Atrial Natriuretic Polypeptide (4-28), human (CAS 95896-08-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com