Loratadine Impurity 55 CAS CATO-C4X-142655
| CAS No. | CATO-C4X-142655 |
| Molecular Formula | C25H29ClN4O |
| Molecular Weight | 436.98 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Loratadine Impurity 55.
As a process- or degradation-related impurity, Loratadine Impurity 55 (CAS CATO-C4X-142655, C25H29ClN4O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C25H29ClN4O, Loratadine Impurity 55 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 436.98 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Loratadine Impurity 55 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H29ClN4O |
| Molecular Weight | 436.98 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Loratadine Standards
- Loratadine Impurity 53 (CAS CATO-C4X-142653)
- Loratadine Impurity 81 (CAS CATO-C4X-142681)
- Loratadine Impurity 43 (CAS CATO-C4X-142643)
- Loratadine Impurity 41 (CAS CATO-C4X-142641)
- Loratadine Impurity 100 (CAS CATO-C4X-1426100)
- Loratadine impurity 21 (CAS CATO-C4X-142621)
- Loratadine impurity 22 (CAS CATO-C4X-142622)
- Loratadine EP Impurity 39 (CAS 609806-38-4)
Recommended Standards
- 4-[(4-Chlorobenzenesulfinyl)methyl]-2-phenyl-6-(phenylsulfanyl)pyrimidine (CAS 306980-55-2)
- Clindamycin Impurity 5 (CAS CATO-C4X-13415)
- 2-(5-((4-Chlorobenzyl)thio)-4-ethyl-4H-1,2,4-triazol-3-yl)thieno[2,3-b]quinoline (CAS 478260-37-6)
- N-Benzyl-4,6-diiodopyrimidin-5-amine (CAS 754190-39-1)
- Etomidate Impurity 71 (CAS CATO-C4X-188471)
- Sildenafil Impurity 278 (CAS CATO-C4X-1128278)
- Fluvoxamine Impurity 156 (CAS CATO-C4X-195156)
- 4-Methoxy-3-[(3-methylphenoxy)methyl]benzoic acid (CAS 438220-78-1)
- 3-(Aminomethyl)-2-hydroxy-2,3-dimethylpentanal (CAS 1539155-33-3)
- (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(pyridin-3-yl)acetic acid (CAS 1259772-07-0)
- Sodium ((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl hydrogen phosphate (CAS 132-00-3)
- N-(6-(Pyrrolidin-1-yl)pyridin-3-yl)chromane-3-carboxamide (CAS 1197538-25-2)
- Cefaclor Ethyl Ester (CAS CATO-C4X-127052)
- Delicious Peptide (bovine) (CAS 73984-05-1)
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