Alprazolam impurity 24 CAS CATO-C4X-146024
| CAS No. | CATO-C4X-146024 |
| Molecular Formula | C15H11Cl2NO2 |
| Molecular Weight | 308.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 308.16 g/mol gives Alprazolam impurity 24 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Alprazolam impurity 24 (CAS CATO-C4X-146024) is a certified pharmaceutical impurity reference standard with the molecular formula C15H11Cl2NO2 and a molecular weight of 308.16 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Alprazolam impurity 24 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 308.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Alprazolam impurity 24 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H11Cl2NO2 |
| Molecular Weight | 308.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Alprazolam Standards
- Alprazolam Impurity 2 (CAS 4016-85-7)
- Alprazolam impurity 25 (CAS CATO-C4X-146025)
- Alprazolam Impurity 26 (CAS CATO-C4X-146026)
- Alprazolam impurity 27 (CAS CATO-C4X-146027)
- Alprazolam EP Impurity G (CAS 448950-89-8)
- Alprazolam (CAS 28981-97-7)
- Alprazolam-D5 (CAS 125229-61-0)
- Alprazolam-D5 (1.0 mg/mL in Methanol) (CAS 1286073-82-2)
Recommended Standards
- N,N'-(1,3,4-Thiadiazole-2,5-diyl)bis(2,2,2-trifluoroacetamide) (CAS 61785-06-6)
- N'-(4-Chlorophenyl)-2-oxo-2-(phenylamino)acetohydrazonoyl chloride (CAS 33101-97-2)
- N-(4-Chloro-2-(3-chlorobenzoyl)phenyl)acetamide (CAS 34999-45-6)
- Pranoprofen Impurity 41 (CAS CATO-C4X-181141)
- Brimonidine Impurity 36 (CAS CATO-C4X-156636)
- Cefoxitin Impurity 23 (CAS CATO-C4X-157823)
- Tenofovir Alafenamide Impurity 36 (CAS CATO-C4X-179736)
- 3-(Aminomethyl)-4-isopropyl-4H-1,2,4-triazole Dihydrochloride (CAS 1258651-61-4)
- Ethyl 3-(3,4-difluorophenyl)-5-methylisoxazole-4-carboxylate (CAS 917388-46-6)
- Indoline-2-carbaldehyde (CAS 412341-32-3)
- 2-(Difluoromethyl)-4-methoxypyridine-6-acetic acid (CAS 1805310-96-6)
- Ethacridine Lactate Impurity 24 (CAS CATO-C4X-260924)
- Lofemizole (CAS 65571-68-8)
- (Glu9)-Exenatide (2-39) trifluoroacetate salt (CAS 196109-34-9)
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