Alprazolam impurity 25 CAS CATO-C4X-146025
| CAS No. | CATO-C4X-146025 |
| Molecular Formula | C15H11Cl2NO2 |
| Molecular Weight | 308.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Alprazolam impurity 25 (C15H11Cl2NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 308.16 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Alprazolam impurity 25 (CAS CATO-C4X-146025), a pharmacopoeial impurity reference standard (molecular formula C15H11Cl2NO2, MW 308.16 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Alprazolam impurity 25 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H11Cl2NO2 |
| Molecular Weight | 308.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Alprazolam Standards
- Alprazolam Impurity 2 (CAS 4016-85-7)
- Alprazolam impurity 24 (CAS CATO-C4X-146024)
- Alprazolam Impurity 26 (CAS CATO-C4X-146026)
- Alprazolam impurity 27 (CAS CATO-C4X-146027)
- Alprazolam EP Impurity G (CAS 448950-89-8)
- Alprazolam (CAS 28981-97-7)
- Alprazolam-D5 (CAS 125229-61-0)
- Alprazolam-D5 (1.0 mg/mL in Methanol) (CAS 1286073-82-2)
Recommended Standards
- N,N'-(1,3,4-Thiadiazole-2,5-diyl)bis(2,2,2-trifluoroacetamide) (CAS 61785-06-6)
- Pranoprofen Impurity 41 (CAS CATO-C4X-181141)
- N'-(4-Chlorophenyl)-2-oxo-2-(phenylamino)acetohydrazonoyl chloride (CAS 33101-97-2)
- Pranoprofen Impurity 59 (CAS CATO-C4X-181159)
- Acarbose EP Impurity A (CAS 1013621-79-8)
- Dotinurad Impurity 208 (CAS 78083-73-5)
- Baclofen Impurity N14 HCl (CAS 204503-99-1)
- 4-Formylphenyl 3,5-dinitrobenzoate (CAS 311330-89-9)
- 2-Aminopyrido[3,4-d]pyrimidin-4(3H)-one (CAS 1434128-52-5)
- 3-Amino-2,2-dimethyl-1-(tetrahydro-2h-pyran-4-yl)propan-1-ol (CAS 1513501-79-5)
- 1-(2-Aminophenyl)piperidine-4-carbonitrile (CAS 1267701-48-3)
- 1-[2-(2-Diethoxyphosphorylethoxy)ethoxy]-2-methoxy-ethane (CAS 915376-46-4)
- 4-(Difluoromethyl)-3,5-diiodopyridine (CAS 1805305-57-0)
- Tirzepatide Impurity 17 (CAS CATO-C4X-324017)
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