Cloperastine Impurity 5 HCl CAS CATO-C4X-15955
| CAS No. | CATO-C4X-15955 |
| Molecular Formula | C20H25NO |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Cloperastine Impurity 5 HCl (CAS CATO-C4X-15955), a pharmacopoeial impurity reference standard (molecular formula C20H25NOHCl, MW 331.88 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Cloperastine Impurity 5 HCl (C20H25NOHCl) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H25NO HCl |
| Molecular Weight | 331.88 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Cloperastine Standards
- Cloperastine impurity 8 (CAS 132301-89-4)
- (R)-Cloperastine (CAS 132301-91-8)
- Cloperastine Hydrochloride (CAS 14984-68-0)
- (S)-Cloperastine Fendizoate (Levocloperastine Fendizoate) (CAS 220329-19-1)
- Cloperastine (CAS 3703-76-2)
- Cloperastine Impurity 2 (CAS 4960-10-5)
- Cloperastine Impurity 1 (CAS 5630-78-4)
- Cloperastine Impurity 3 (CAS 6954-45-6)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com