Riociguat Impurity 43 HCl CAS CATO-C4X-174943
| CAS No. | CATO-C4X-174943 |
| Molecular Formula | C14H13N5 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Riociguat Impurity 43 HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Riociguat Impurity 43 HCl (CAS CATO-C4X-174943) is a certified pharmaceutical impurity reference standard with the molecular formula C14H13N5HCl and a molecular weight of 287.75 g/mol.
Structurally, Riociguat Impurity 43 HCl (C14H13N5HCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 287.75 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C14H13N5 HCl |
| Molecular Weight | 287.75 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Riociguat Standards
- Riociguat-13C-d3 (CAS 1304478-43-0)
- Riociguat Impurity 2 (CAS 1361569-10-9)
- Riociguat Impurity 16 (CAS 1361569-18-7)
- Riociguat Impurity 18 (CAS 1361569-23-4)
- Riociguat Impurity 1 (CAS 1702271-98-4)
- Riociguat Impurity N10 (CAS 2101651-50-5)
- Riociguat Impurity N3 (CAS 2512205-25-1)
- Riociguat Impurity 30 (CAS 2518331-19-4)
Recommended Standards
- Citalopram Impurity 70 (CAS 1332724-08-9)
- Naproxen EP Impurity F (CAS 31220-35-6)
- Valproate Impurity 84 (CAS CATO-C4X-116684)
- 5-Hydroxy-3,4-dimethylfuran-2(5H)-one (CAS 1575-54-8)
- 2-(2-{[(tert-butoxy)carbonyl]amino}cyclohexyl)acetic acid (CAS 1781118-70-4)
- 4-(Chloromethyl)-4-methyltetrahydro-2h-pyran (CAS 1466745-29-8)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperidin-3-amine hydrochloride (CAS 1185313-62-5)
- 1-Methyl-1,2,3,4-tetrahydroquinolin-7-amine (CAS 304690-94-6)
- 2,2-Dimethyl-5-propionylcyclopentan-1-one (CAS 1542692-65-8)
- Semaglutide impurity 58 (CAS CATO-C4X-222658)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com