Trazodone Impurity 101 TriHCl CAS CATO-C4X-1772101
| CAS No. | CATO-C4X-1772101 |
| Molecular Formula | C16H19Cl2N3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Trazodone Impurity 101 TriHCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Trazodone Impurity 101 TriHCl (CAS CATO-C4X-1772101), a pharmacopoeial impurity reference standard (molecular formula C16H19Cl2N3HClHClHCl, MW 433.62 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Trazodone Impurity 101 TriHCl (C16H19Cl2N3HClHClHCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 433.62 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C16H19Cl2N3 HCl HCl HCl |
| Molecular Weight | 433.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Trazodone Standards
- Trazodone Impurity N13 (CAS 101364-27-6)
- Trazodone D6 (CAS 1181578-48-2)
- Trazodone-d6 Hydrochloride (CAS 1181578-71-1)
- Trazodone Hydrochloride EP Impurity C (CAS 1263278-77-8)
- Trazodone Impurity 4 (CAS 1263278-79-0)
- Trazodone EP Impurity D HCl (CAS 1263278-80-3)
- Trazodone Hydrochloride EP Impurity J (CAS 1263358-12-8)
- Trazodone EP Impurity D (CAS 1263358-13-9)
Recommended Standards
- Imipenem Impurity 102 (CAS CATO-C4X-1662102)
- Nicorandil Impurity 51 HCl (CAS CATO-C4X-190751)
- Lornoxicam impurity 59 (CAS CATO-C4X-201659)
- 2,2'-(1,3,4,-Oxadiazole-2,5-diyl)bis[1-amino-9,10-anthracenedione (CAS 52591-25-0)
- Methyl 2-(4-(3-(4-chlorophenyl)ureido)phenoxy)benzoate (CAS 865660-46-4)
- 1-Boc-3-(Fmoc-amino)-3-piperidinecarboxylic Acid (CAS 368866-21-1)
- 5-((Isopropylamino)methyl)pyridin-3-ylboronic acid hydrochloride (CAS 1425335-02-9)
- 6-Acetyl-1H,3H-benzo[de]isochromene-1,3-dione (CAS 1146-72-1)
- 1-(2-Methylpropyl)cyclopropan-1-amine hydrochloride (CAS 1255717-83-9)
- D-Lys20-Tirzepatide (CAS CATO-CPTD788914)
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