Trazodone impurity 63 CAS CATO-C4X-177263
| CAS No. | CATO-C4X-177263 |
| Molecular Formula | C16H24Cl3N2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Trazodone impurity 63 (CAS CATO-C4X-177263), a pharmacopoeial impurity reference standard (molecular formula C16H24Cl3N2Br, MW 430.64 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/bromine substitution, Trazodone impurity 63 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 430.64 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H24Cl3N2 Br |
| Molecular Weight | 430.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related Trazodone Standards
- Trazodone Impurity N13 (CAS 101364-27-6)
- Trazodone D6 (CAS 1181578-48-2)
- Trazodone-d6 Hydrochloride (CAS 1181578-71-1)
- Trazodone Hydrochloride EP Impurity C (CAS 1263278-77-8)
- Trazodone Impurity 4 (CAS 1263278-79-0)
- Trazodone EP Impurity D HCl (CAS 1263278-80-3)
- Trazodone Hydrochloride EP Impurity J (CAS 1263358-12-8)
- Trazodone EP Impurity D (CAS 1263358-13-9)
Recommended Standards
- Nintedanib Impurity 147 (CAS CATO-C4X-1814147)
- Teprenone impurity 35 (CAS CATO-C4X-208135)
- Cinepazide Impurity 9 (CAS 1352050-81-7)
- 3-(1-nitroso-1H-indol-3-yl)propanoic acid (CAS 769186-79-0)
- 2-Methoxy-N-(5-(2-methoxyphenyl)-1,3,4-thiadiazol-2-yl)benzamide (CAS 701227-09-0)
- 1-(3,4-Dichlorophenyl)cyclohexane-1-carboxylic acid (CAS 162733-00-8)
- Methyl (5-hydroxy-1-pyridin-2-yl-1H-pyrazol-3-yl)acetate (CAS 1119391-01-3)
- 6,7-Difluoro-1H-indole (CAS 271780-84-8)
- N-(2-(3-Acetyl-2-methylindolizin-1-yl)propyl)-N,N-dimethylbutan-1-aminium iodide (CAS 66902-73-6)
- Semaglutide impurity 233 (CAS CATO-C4X-2226233)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com