Nintedanib Impurity 134 CAS CATO-C4X-1814134
| CAS No. | CATO-C4X-1814134 |
| Molecular Formula | C18H30N6O |
| Molecular Weight | 346.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Nintedanib Impurity 134 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Nintedanib Impurity 134 (CAS CATO-C4X-1814134, C18H30N6O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C18H30N6O, Nintedanib Impurity 134 contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 346.47 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Nintedanib Impurity 134 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H30N6O |
| Molecular Weight | 346.47 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
Related Nintedanib Standards
- Nintedanib Impurity 119 (CAS CATO-C4X-1814119)
- Nintedanib Impurity 99 (CAS CATO-C4X-181499)
- Nintedanib Impurity 128 (CAS CATO-C4X-1814128)
- Nintedanib Impurity 13 (CAS 1253769-13-9)
- Nintedanib Impurity 49 (CAS 1168152-07-5)
- Nintedanib Impurity 148 (CAS CATO-C4X-1814148)
- Nintedanib Impurity 162 (CAS CATO-C4X-1814162)
- Nintedanib Impurity 26 (CAS CATO-C4X-181426)
Recommended Standards
- tert-Butyl 4-(4-(pyridin-2-yl)piperazin-1-yl)piperidine-1-carboxylate (CAS 864685-07-4)
- Evocalcet impurity 57 (CAS CATO-C4X-248557)
- N,3,3-trimethyl-2-(2-(4-phenylpiperazin-1-yl)acetamido)butanamide (CAS 318949-38-1)
- Evocalcet Impurity 62 (CAS CATO-C4X-248562)
- Empagliflozin Impurity 93 (CAS 19932-79-7)
- Fluconazole Impurity 56 (CAS CATO-C4X-101956)
- Eprazinone Impurity 1 (CAS CATO-C4X-33111)
- (4-((Tert-butoxycarbonyl)amino)bicyclo[2.2.2]Octan-1-yl)methyl 4-(trifluoromethyl)benzenesulfonate (CAS 2173992-16-8)
- 1-(4-Butylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol (CAS 1416342-65-8)
- 4-(3-Iodoanilino)-4-oxobutanoic acid (CAS 62134-53-6)
- N-(2-bromophenyl)-2-((1-methyl-1H-imidazol-2-yl)thio)acetamide (CAS 457078-71-6)
- 3-Amino-1H-pyrrolo[3,2-b]pyridin-6-ol (CAS 1190313-34-8)
- 3-Bromo-6-chloro-2-fluorophenoxy(tert-butyl)dimethylsilane (CAS 1881320-40-6)
- Des-Lys20(Side Chain)-Semaglutide (CAS CATO-C4X-2226280)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com