Nebivolol Impurity 55 CAS CATO-C4X-196855
| CAS No. | CATO-C4X-196855 |
| Molecular Formula | C18H21NO2 |
| Molecular Weight | 283.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Nebivolol Impurity 55 (CAS CATO-C4X-196855) is a certified pharmaceutical impurity reference standard with the molecular formula C18H21NO2 and a molecular weight of 283.36 g/mol.
Structurally, Nebivolol Impurity 55 (C18H21NO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 283.36 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Nebivolol Impurity 55 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H21NO2 |
| Molecular Weight | 283.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Nebivolol Standards
- Nebivolol Impurity 54 (CAS CATO-C4X-196854)
- Nebivolol Impurity 67 (CAS CATO-C4X-196867)
- Nebivolol Impurity 70 (CAS CATO-C4X-196870)
- Nebivolol Impurity 75 (CAS CATO-C4X-196875)
- Nebivolol Impurity 14 (CAS 129050-29-9)
- Nebivolol Impurity 15 (CAS 1029684-20-5)
- Nebivolol Impurity 64 (CAS CATO-C4X-196864)
- Nebivolol Impurity 65 (CAS CATO-C4X-196865)
Recommended Standards
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