Cabozantinib Impurity 23 CAS CATO-C4X-201823
| CAS No. | CATO-C4X-201823 |
| Molecular Formula | C18H16F2N2O2 |
| Molecular Weight | 330.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Cabozantinib Impurity 23 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Cabozantinib Impurity 23 (CAS CATO-C4X-201823) is a certified pharmaceutical impurity reference standard with the molecular formula C18H16F2N2O2 and a molecular weight of 330.33 g/mol.
Based on its molecular formula C18H16F2N2O2, Cabozantinib Impurity 23 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 330.33 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C18H16F2N2O2 |
| Molecular Weight | 330.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Cabozantinib Standards
- Cabozantinib Impurity 2 (CAS 190728-24-6)
- Cabozantinib Impurity 48 (CAS CATO-C4X-201848)
- Cabozantinib Impurity 50 (CAS CATO-C4X-201850)
- Cabozantinib Impurity N3 (CAS 651054-52-3)
- Cabozantinib Impurity 3 (CAS 1431468-36-8)
- Cabozantinib Impurity 5 (CAS 849217-60-3)
- Cabozantinib Impurity 42 (CAS CATO-C4X-201842)
- Cabozantinib Impurity 8 (CAS 213699-53-7)
Recommended Standards
- Oseltamivir Impurity 158 (CAS CATO-C4X-1720158)
- Acetylshikonin (CAS 24502-78-1)
- Oseltamivir Impurity 157 (CAS CATO-C4X-1720157)
- 3-methyl-1-phenyl-6-pyridin-3-yl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1011397-14-0)
- Bromphenamine Impurity 2 (CAS CATO-C4X-29982)
- Famotidine EP Impurity C HCl (CAS 76824-17-4)
- Cefuroxime Impurity 79 (CAS CATO-C4X-124579)
- 2-(2-Methylcyclopropyl)-6-oxo-1,6-dihydropyrimidine-5-carboxylic acid (CAS 1482454-96-5)
- 3-(1-Bromo-8-chloroimidazo[1,5-a]pyrazin-3-yl)cyclobutan-1-one (CAS 936901-73-4)
- 5-Formyl-2',3'-O-(1-methylethylidene)-cytidine (CAS 153535-36-5)
- 5-Bromo-4-hydrazinyl-2-(methylthio)pyrimidine (CAS 875-96-7)
- 2-(4-Piperidinyl)ethyl benzoate hydrochloride (CAS 1220021-15-7)
- Sodium 2-Octyl-1-docecyl Sulfate (CAS 78204-54-3)
- Des-Ile12-Aib13-Tirzepatide (CAS CATO-CPTD788960)
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