Abemaciclib Impurity 59 CAS CATO-C4X-293759
| CAS No. | CATO-C4X-293759 |
| Molecular Formula | C27H30F2N8O |
| Molecular Weight | 520.58 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Abemaciclib Impurity 59 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 520.58 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Abemaciclib Impurity 59 (CAS CATO-C4X-293759), a pharmacopoeial impurity reference standard (molecular formula C27H30F2N8O, MW 520.58 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Abemaciclib Impurity 59 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C27H30F2N8O |
| Molecular Weight | 520.58 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 8 |
Related Abemaciclib Standards
- Abemaciclib Impurity 137 (CAS CATO-C4X-2937137)
- Abemaciclib Impurity 138 (CAS CATO-C4X-2937138)
- Abemaciclib Impurity 103 (CAS CATO-C4X-2937103)
- Abemaciclib Impurity 80 (CAS CATO-C4X-293780)
- Abemaciclib Impurity 81 (CAS CATO-C4X-293781)
- Abemaciclib Impurity 84 (CAS CATO-C4X-293784)
- Abemaciclib Impurity 134 (CAS CATO-C4X-2937134)
- Abemaciclib Impurity 17 (CAS CATO-C4X-293717)
Recommended Standards
- Ensifentrine impurity 14 (CAS CATO-C4X-335314)
- (Tyr0,Trp2)-Melanocyte-Stimulating Hormone-Release Inhibiting Factor (CAS 144450-13-5)
- Tolvaptan Impurity 62 (CAS 2657689-30-8)
- (4AR,6S,7R,8S,8aS)-7-acetoxy-2-phenyl-6-(p-tolylthio)hexahydropyrano[3,2-d][1,3]dioxin-8-yl benzoate (CAS 1042430-52-3)
- Sitafloxacin impurity 58 (CAS CATO-C4X-115558)
- Asciminib Impurity N1 (CAS 1492952-73-4)
- Oxytocin Impurity 44 (CAS CATO-C4X-206644)
- 4-{[1-(4-methoxyphenyl)acetamido]methyl}benzoic acid (CAS 925137-96-8)
- 2,6-Bis(3,5-dichlorophenyl)-4-hydroxydinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepine 4-sulfide (CAS 1706463-50-4)
- (S)-2-(2-Acetyl-5-methyloxazole-4-carboxamido)propanoic acid (CAS 61183-10-6)
- 4-(Cyanomethoxy)benzoic acid (CAS 792954-24-6)
- 1-phenyl-1H-pyrrolo[3,2-b]pyridine-3-carboxylic acid (CAS 1498196-17-0)
- Nicorandil Impurity 9 (CAS 2250142-71-1)
- Tau Peptide (379-408) trifluoroacetate salt (CAS 1246357-53-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com