Abemaciclib Impurity 24 CAS CATO-C4X-293724
| CAS No. | CATO-C4X-293724 |
| Molecular Formula | C6H6N2O3 |
| Molecular Weight | 154.12 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Abemaciclib Impurity 24 (CAS CATO-C4X-293724), a pharmacopoeial impurity reference standard (molecular formula C6H6N2O3, MW 154.12 g/mol) used for the identification and quantification of trace impurities in APIs.
Abemaciclib Impurity 24 (C6H6N2O3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C6H6N2O3 |
| Molecular Weight | 154.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Abemaciclib Standards
- Abemaciclib Impurity 40 (CAS CATO-C4X-293740)
- Abemaciclib Impurity 27 (CAS 22462-34-6)
- Abemaciclib impurity 115 (CAS CATO-C4X-2937115)
- Abemaciclib impurity 116 (CAS CATO-C4X-2937116)
- Abemaciclib impurity 104 (CAS 150807-86-6)
- Abemaciclib Impurity 2 (CAS 1528469-78-4)
- Abemaciclib Impurity 36 (CAS CATO-C4X-293736)
- Abemaciclib Impurity 7 (CAS 414881-11-1)
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- Regadenoson Impurity 4 (CAS CATO-C4X-19854)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com