Dabrafenib Impurity 23 CAS CATO-C4X-303323

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-303323
Molecular FormulaC17H13FIN3O4
Molecular Weight469.21 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Dabrafenib Impurity 23 CAS CATO-C4X-303323 chemical structure

Description

CATO supplies Dabrafenib Impurity 23 (CAS CATO-C4X-303323), a pharmacopoeial impurity reference standard (molecular formula C17H13FIN3O4, MW 469.21 g/mol) used for the identification and quantification of trace impurities in APIs.

Based on its molecular formula C17H13FIN3O4, Dabrafenib Impurity 23 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine/iodine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 469.21 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Dabrafenib Impurity 23 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC17H13FIN3O4
Molecular Weight469.21 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity>95%
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentF/I-containing
Nitrogen Atoms3

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