Nebivolol Impurity 14 CAS 129050-29-9
| CAS No. | 129050-29-9 |
| Molecular Formula | C17H18FNO2 |
| Molecular Weight | 287.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Nebivolol Impurity 14 (CAS 129050-29-9, C17H18FNO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Nebivolol Impurity 14 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 287.33 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Nebivolol Impurity 14 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H18FNO2 |
| Molecular Weight | 287.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Nebivolol Standards
- Nebivolol Impurity 15 (CAS 1029684-20-5)
- Nebivolol Impurity 67 (CAS CATO-C4X-196867)
- Nebivolol Impurity 70 (CAS CATO-C4X-196870)
- Nebivolol Impurity 75 (CAS CATO-C4X-196875)
- Nebivolol Impurity 54 (CAS CATO-C4X-196854)
- Nebivolol Impurity 55 (CAS CATO-C4X-196855)
- Nebivolol Impurity 16 (CAS 99199-91-4)
- Nebivolol Impurity 56 (CAS CATO-C4X-196856)
Recommended Standards
- Ciprofloxacin EP Impurity E (CAS 105394-83-0)
- Tirofiban Impurity 108 (CAS 1103300-75-9)
- D-p-Methyl Sulfone Phenyl Ethyl Serinate (CAS 36983-12-7)
- Amisulpride Impurity 42 (CAS 31925-29-8)
- Pentoxifylline EP Impurity H(DiHCl) (CAS CATO-C4X-17288)
- Dapagliflozin Impurity 141 (CAS 1629862-21-0)
- Testosterone Impurity 75 (CAS CATO-C4X-243275)
- Ketorolac Impurity 52 (CAS 147088-89-9)
- Dimethyl 2-ethynylterephthalate (CAS 1360461-76-2)
- Etelcalcetide Impurity 27 X TFA Salt (CAS CATO-C4X-324727)
- Methyl(pyridin-3-ylmethyl)(pyrrolidin-3-ylmethyl)amine hydrochloride (CAS 1420809-95-5)
- Ethyl 2-phenyl-4-{[3-(trifluoromethyl)phenyl]sulfanyl}pyrimidine-5-carboxylate (CAS 477854-56-1)
- N-(3-isobutoxypropyl)thietan-3-amine (CAS 1863672-24-5)
- Semaglutide impurity 27 (CAS CATO-C4X-222627)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com