Nebivolol Impurity 56 CAS CATO-C4X-196856
| CAS No. | CATO-C4X-196856 |
| Molecular Formula | C18H20FNO2 |
| Molecular Weight | 301.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 301.36 g/mol gives Nebivolol Impurity 56 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Nebivolol Impurity 56 (CAS CATO-C4X-196856) is a certified pharmaceutical impurity reference standard with the molecular formula C18H20FNO2 and a molecular weight of 301.36 g/mol.
Nebivolol Impurity 56 (C18H20FNO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Nebivolol Impurity 56 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H20FNO2 |
| Molecular Weight | 301.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Nebivolol Standards
- Nebivolol Impurity 16 (CAS 99199-91-4)
- Nebivolol Impurity 14 (CAS 129050-29-9)
- Nebivolol Impurity 15 (CAS 1029684-20-5)
- Nebivolol Impurity 67 (CAS CATO-C4X-196867)
- Nebivolol Impurity 70 (CAS CATO-C4X-196870)
- Nebivolol Impurity 75 (CAS CATO-C4X-196875)
- Nebivolol Impurity 54 (CAS CATO-C4X-196854)
- Nebivolol Impurity 55 (CAS CATO-C4X-196855)
Recommended Standards
- Sotalol impurity 6 (CAS 134720-07-3)
- Diltiazem EP Impurity E (CAS 42399-49-5)
- Sotalol Impurity 9 (CAS CATO-C4X-20929)
- Diltiazem Impurity 21 (CAS 42399-51-9)
- Procaterol Impurity 1 (CAS 59827-93-9)
- BRD9 Impurity 3 (CAS 2704617-96-7)
- Travoprost Impurity 23 (CAS CATO-C4X-192523)
- Mepyramine N-Oxide (CAS 98982-99-1)
- 2-Chloro-6-isopropylpyridine-3-boronic acid pinacol ester (CAS 1689528-51-5)
- 2-(Dodecyloxy)-6-hydroxyanthracene-9,10-dione (CAS 157466-90-5)
- Revefenacin Impurity 47 (CAS CATO-C4X-203147)
- Perivine (CAS 2673-40-7)
- (R)-2,2,2-Trifluoro-1-(3-(trifluoromethyl)phenyl)ethanamine hydrochloride (CAS 1391469-75-2)
- Semaglutide impurity 251 (CAS CATO-C4X-2226251)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com