Verapamil EP Impurity L CAS 14046-55-0
| CAS No. | 14046-55-0 |
| Molecular Formula | C12H16O3 |
| Molecular Weight | 208.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Verapamil EP Impurity L (CAS 14046-55-0), a pharmacopoeial impurity reference standard (molecular formula C12H16O3, MW 208.25 g/mol) used for the identification and quantification of trace impurities in APIs.
Verapamil EP Impurity L (C12H16O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Verapamil EP Impurity L under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H16O3 |
| Molecular Weight | 208.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
Related Verapamil Standards
- Verapamil EP Impurity C (CAS 3490-05-9)
- Verapamil EP Impurity K (CAS 20850-49-1)
- Verapamil EP Impurity B (CAS 3490-06-0)
- Verapamil Impurity 25 (CAS 3893-01-4)
- Verapamil Impurity 27 (CAS 7306-46-9)
- Verapamil Impurity 49 (CAS CATO-C4X-177849)
- Verapamil Impurity 52 (CAS CATO-C4X-177852)
- Verapamil Impurity 24 (CAS 18086-24-3)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com