Verapamil EP Impurity B CAS 3490-06-0
| CAS No. | 3490-06-0 |
| Molecular Formula | C11H17NO2 |
| Molecular Weight | 195.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Verapamil EP Impurity B (CAS 3490-06-0), a pharmacopoeial impurity reference standard (molecular formula C11H17NO2, MW 195.26 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Verapamil EP Impurity B (C11H17NO2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 195.26 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Verapamil EP Impurity B meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H17NO2 |
| Molecular Weight | 195.26 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
Related Verapamil Standards
- Verapamil Impurity 25 (CAS 3893-01-4)
- Verapamil Impurity 27 (CAS 7306-46-9)
- Verapamil EP Impurity L (CAS 14046-55-0)
- Verapamil EP Impurity C (CAS 3490-05-9)
- Verapamil Impurity 24 (CAS 18086-24-3)
- Verapamil EP Impurity K (CAS 20850-49-1)
- Verapamil Hydrochloride EP Impurity E (CAS 93-03-8)
- Verapamil EP Impurity G (CAS 120-14-9)
Recommended Standards
- Mirtazapine Impurity 27 (CAS 85141-93-1)
- Dopamine impurity 120 (CAS 3490-09-3)
- Loratadine Impurity 71 (CAS CATO-C4X-142671)
- Mexiletine Impurity 4 (CAS 57204-78-1)
- Raloxifene Impurity 3 (CAS 1677681-02-5)
- Mirogabalin Impurity 143 (CAS CATO-C4X-2924143)
- Grapiprant Impurity 3 (CAS 415907-78-7)
- Lapatinib Impurity 9 (CAS 1393175-04-6)
- Bis(2-ethylhexyl) succinate (CAS 2915-57-3)
- 2-Cyclobutylbut-3-yn-2-ol (CAS 515-81-1)
- (R)-Vestitol (CAS 35878-41-2)
- 5-Bromo-4,6-dimethoxybenzo[d][1,3]dioxole (CAS 2169908-22-7)
- Sulfasymazine (CAS 1984-94-7)
- Semaglutide impurity 30 (CAS CATO-C4X-222630)
Why CATO?
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