Nebivolol Impurity 44 CAS 18867-45-3
| CAS No. | 18867-45-3 |
| Molecular Formula | C11H16N2O4 |
| Molecular Weight | 240.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Nebivolol Impurity 44.
CATO supplies Nebivolol Impurity 44 (CAS 18867-45-3), a certified reference material (molecular formula C11H16N2O4, MW 240.26 g/mol) for analytical method development and quality control.
Nebivolol Impurity 44 (C11H16N2O4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Nebivolol Impurity 44 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H16N2O4 |
| Molecular Weight | 240.26 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Nitrogen Atoms | 2 |
Related Nebivolol Standards
- Nebivolol Impurity 66 (CAS 1017878-67-9)
- Nebivolol Impurity 72 (CAS CATO-C4X-196872)
- Nebivolol Impurity 73 (CAS CATO-C4X-196873)
- Nebivolol Impurity 23 (CAS CATO-C4X-196823)
- Nebivolol Impurity 24 (CAS CATO-C4X-196824)
- Nebivolol Impurity 27 (CAS CATO-C4X-196827)
- Nebivolol Impurity 68 (CAS CATO-C4X-196868)
- Nebivolol Impurity 71 (CAS CATO-C4X-196871)
Recommended Standards
- Tert-butyl 4,6-dioxohexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate (CAS 1860231-51-1)
- 3-(5H-Pyrido[4,3-b]indol-7-yl)propanoic acid (CAS 1892461-96-9)
- tert-Butyl 1-(2-methoxy-2-oxoethyl)-1H-pyrazole-5-carboxylate (CAS 1855907-27-5)
- 2-(4-Methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyridin-7-amine (CAS 1894480-74-0)
- 2-{8-methyl-8-azabicyclo[3.2.1]octan-3-ylidene}acetic acid hydrochloride (CAS 123368-82-1)
- (3-Methoxy-2-methyl-2H-indazol-6-yl)(morpholino)methanone (CAS 1421462-48-7)
- 5,5-Difluoro-10-(4-hydroxyphenyl)-1,3,9-trimethyl-7-((1E,3E)-3-(1,3,3-trimethylindolin-2-ylidene)prop-1-en-1-yl)-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide (CAS 1403241-74-6)
- 3-Hydroxy-5-(trifluoromethyl)benzonitrile (CAS 1243459-56-4)
- 2,3-Dimethylisonicotinaldehyde (CAS 867141-55-7)
- 1-Chloro-2-(methylsulfonyl)-4-nitrobenzene (CAS 21081-74-3)
- n-(2-Hydroxyethyl)-3-(2-oxopyridin-1(2h)-yl)propanamide (CAS 1153282-25-7)
- (1R,2R,4S)-2-amino-1,7,7-trimethylbicyclo[2.2.1]Heptane-2-carboxylic acid hydrochloride (CAS 1955474-97-1)
- Glipizide Impurity 18 (CAS 122-05-4)
- D-Gln19-Tirzepatide (CAS CATO-CPTD788915)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com