Fosaprepitant impurity 58 CAS CATO-C4X-116858
| CAS No. | CATO-C4X-116858 |
| Molecular Formula | C37H34F7N4O6P |
| Molecular Weight | 794.65 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Fosaprepitant impurity 58 (CAS CATO-C4X-116858), a pharmacopoeial impurity reference standard (molecular formula C37H34F7N4O6P, MW 794.65 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Fosaprepitant impurity 58 (C37H34F7N4O6P) contains a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 19.5, corresponding to approximately 19 ring(s) or double-bond equivalent(s). With a molecular weight of 794.65 g/mol, it falls into the high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Fosaprepitant impurity 58 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C37H34F7N4O6P |
| Molecular Weight | 794.65 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 19.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Fosaprepitant Standards
- Fosaprepitant Impurity 20 (CAS CATO-C4X-116820)
- Fosaprepitant Impurity 21 (CAS 265121-01-5)
- Fosaprepitant Impurity 51 (CAS CATO-C4X-116851)
- Fosaprepitant Impurity 12 (CAS 2035475-10-4)
- Fosaprepitant Impurity 22 (CAS CATO-C4X-116822)
- Fosaprepitant Impurity 42 (CAS CATO-C4X-116842)
- Fosaprepitant Impurity 44 (CAS CATO-C4X-116844)
- Fosaprepitant Impurity 45 (CAS CATO-C4X-116845)
Recommended Standards
- 2,3-Dibromo-1,4-dichlorobutane (CAS 4911-46-0)
- 5,10,15,20-Tetrakis(4-nitrophenyl)porphyrin (CAS 22843-73-8)
- Dichloro [(R)-(+)-2,2-bis(diphenylphosphino)-1,1-binaphathyl] ruthenium(II) (CAS 132071-87-5)
- meso-Tetra(2-nitrophenyl) porphine (CAS 37116-82-8)
- Suzetrigine Impurity 24 (CAS 3083330-03-1)
- Evocalcet Impurity 24 (CAS CATO-C4X-248524)
- Propofol EP Impurity L (CAS 201166-22-5)
- Mn(dtbpy)2OTf2 (CAS 2649421-47-4)
- 3-(azepan-1-yl)propanethioamide (CAS 100705-02-0)
- 2-Amino-2-(3-chloro-4,5-dimethoxyphenyl)acetic acid hydrochloride (CAS 1137087-15-0)
- (2S)-2-Amino-N-((1-benzylpiperidin-3-yl)methyl)-3-methylbutanamide (CAS 1354025-17-4)
- 3-(2-Cyanophenyl)acrylic acid methyl ester (CAS 18524-80-6)
- Levonorgestrel Acetate Delta-5 Impurity (CAS 1175110-92-5)
- Galanin-Like Peptide (porcine) trifluoroacetate salt (CAS 245114-96-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com