Ibrutinib Impurity 66 HCl CAS CATO-C4X-106466
| CAS No. | CATO-C4X-106466 |
| Molecular Formula | C22H22N6O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Ibrutinib Impurity 66 HCl (CAS CATO-C4X-106466) is a certified pharmaceutical impurity reference standard with the molecular formula C22H22N6OHCl and a molecular weight of 422.92 g/mol.
Structurally, Ibrutinib Impurity 66 HCl (C22H22N6OHCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 422.92 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Ibrutinib Impurity 66 HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H22N6O HCl |
| Molecular Weight | 422.92 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
Related Ibrutinib Standards
- Ibrutinib Impurity 47 (CAS 1022150-11-3)
- Ibrutinib Impurity 10 (CAS 1022150-12-4)
- Ibrutinib Impurity 80 (CAS 109384-19-2)
- Ibrutinib Impurity 53 (CAS 109831-68-7)
- Ibrutinib Impurity 54 (CAS 1260862-85-8)
- Ibrutinib Impurity 4 (CAS 1288338-95-3)
- Ibrutinib Impurity 3 (CAS 1288338-96-4)
- Ibrutinib Impurity 81 (CAS 143667-36-1)
Recommended Standards
- Bicalutamide EP Impurity F (CAS CATO-C4X-101326)
- Niflumic acid impurity 2 (CAS CATO-C4X-30852)
- Linezolid Impurity 122 (CAS CATO-C4X-1073122)
- (E)-3-(4-methoxy-3-((3,4,5-trimethyl-1H-pyrazol-1-yl)methyl)phenyl)acrylic acid (CAS 1173492-85-7)
- 6-Ethyl-5,7-difluoroindoline-2,3-dione (CAS 749241-79-0)
- 1-(5-(4-Amino-2-chlorophenyl)furan-2-yl)ethanone (CAS 886494-56-0)
- 2,4,6-Trimethylbenzyl Bromide (CAS 4761-00-6)
- Methyl 7-((1S,2S)-2-octylcyclopentyl)heptanoate (CAS 1001-80-5)
- Citalopram Impurity 23 (CAS 1217846-85-9)
- Met(O)14-Exenatide trifluoroacetate salt (CAS 1678417-38-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com