Canagliflozin Impurity 92 CAS CATO-C4X-112392

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-112392
Molecular FormulaC18H12FIS
Molecular Weight406.26 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Canagliflozin Impurity 92 CAS CATO-C4X-112392 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Canagliflozin Impurity 92.

Canagliflozin Impurity 92 (CAS CATO-C4X-112392) is a certified pharmaceutical impurity reference standard with the molecular formula C18H12FIS and a molecular weight of 406.26 g/mol.

The molecular framework of Canagliflozin Impurity 92 (C18H12FIS) is characterized by sulfur-containing functionality, fluorine/iodine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Canagliflozin Impurity 92 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC18H12FIS
Molecular Weight406.26 g/mol
Purity97%+
StorageStore at room temperature, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentF/I-containing
Sulfur Atoms1

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