Dapagliflozin Impurity 128 CAS CATO-C4X-1138128
| CAS No. | CATO-C4X-1138128 |
| Molecular Formula | C15H14ClIO |
| Molecular Weight | 372.63 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Dapagliflozin Impurity 128.
Dapagliflozin Impurity 128 (CAS CATO-C4X-1138128) is a certified pharmaceutical impurity reference standard with the molecular formula C15H14ClIO and a molecular weight of 372.63 g/mol.
Dapagliflozin Impurity 128 (C15H14ClIO) contains a hydroxyl group, an ether linkage, chlorine/iodine substitution, a polycyclic aromatic system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H14ClIO |
| Molecular Weight | 372.63 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl/I-containing |
Related Dapagliflozin Standards
- Dapagliflozin Impurity 127 (CAS CATO-C4X-1138127)
- Dapagliflozin Impurity 26 (CAS 2305949-36-2)
- Dapagliflozin Impurity 68 (CAS 1103738-29-9)
- Dapagliflozin Impurity 129 (CAS CATO-C4X-1138129)
- Dapagliflozin Impurity 180 (CAS CATO-C4X-1138180)
- Dapagliflozin Impurity 32 (CAS 2452300-89-7)
- Dapagliflozin Impurity 12 (CAS 1807632-93-4)
- Dapagliflozin Impurity 143 (CAS CATO-C4X-1138143)
Recommended Standards
- Empagliflozin impurity 208 (CAS CATO-C4X-1065208)
- Empagliflozin Impurity 102 (CAS CATO-C4X-1065102)
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- 1-(2-bromophenyl)-N-methyl-2-propanamine 1-(2-bromophenyl)-N-methyl-propan-2-amine 466-37-5 A827086 (CAS 466-37-5)
- Ornidazole Impurity 15 (CAS 105687-87-4)
- Enzalutamide Impurity 40 (CAS 3079438-61-9)
- Difamilast Impurity 3 (CAS 937782-02-0)
- Dapagliflozin Impurity 45 (CAS 864070-18-8)
- 1-(2-Fluorobenzyl)-3-iodo-1H-pyrazolo[3,4-d]pyrimidine (CAS 1446712-64-6)
- 123065-34-9 4-n-Butoxybenzenesulfinic acid sodium salt MFCD11618023 (CAS 123065-34-9)
- 1-(2-chlorophenyl)-5-(difluoromethyl)-3-methyl-1H-pyrazole-4-carboxylic acid (CAS 1375473-93-0)
- 1-((2R,3R,4S,5R)-3-Amino-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione (CAS 174221-86-4)
- (Z)-2-fluoro-N'-hydroxybenzene-1-carboximidamide (CAS 1422554-22-0)
- Semaglutide impurity 77 (CAS CATO-C4X-222677)
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