Fosaprepitant Impurity 24 CAS CATO-C4X-116824
| CAS No. | CATO-C4X-116824 |
| Molecular Formula | C23H22F7N4O6P |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Fosaprepitant Impurity 24 (CAS CATO-C4X-116824), a pharmacopoeial impurity reference standard (molecular formula C23H22F7N4O6PC7H17NO5, MW 809.63 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, fluorine substitution, Fosaprepitant Impurity 24 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 809.63 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Fosaprepitant Impurity 24 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H22F7N4O6P 2*C7H17NO5 |
| Molecular Weight | 809.63 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related Fosaprepitant Standards
- Fosaprepitant impurity 55（R,S,R） (CAS 1185503-00-7(free base))
- Fosaprepitant Impurity 53 (CAS 1254261-32-9)
- Fosaprepitant Impurity 4 Dimeglumine (CAS 1523569-87-0)
- Fosaprepitant Impurity 19 (CAS 1623-07-0)
- Fosaprepitant Impurity 48 (CAS 1707-92-2)
- Fosaprepitant Impurity 6 (CAS 172822-01-4（free base）)
- Fosaprepitant Impurity 12 (CAS 2035475-10-4)
- Fosaprepitant Impurity 41 HCl (CAS 2377328-02-2)
Recommended Standards
- Capecitabine Impurity 43 (CAS CATO-C4X-102443)
- Carbidopa Impurity 21 (CAS CATO-C4X-231021)
- Levofloxacin Impurity 32 (CAS 1329833-82-0)
- N,N-diethyl-2-nitro-4-(trifluoromethyl)aniline (CAS 254754-76-2)
- 2,4-Dimethyl 5-[bis(phenylcarbamoyl)amino]-3-(2-methoxy-2-oxoethyl)thiophene-2,4-dicarboxylate (CAS 339020-08-5)
- 5-Acetyl-2-((3-fluorobenzyl)oxy)benzoic acid (CAS 1416343-00-4)
- 4-Amino-7-chloro-6-fluorocinnoline-3-carboxylic acid (CAS 159831-73-9)
- Nimodipine Impurity 47 (CAS CATO-C4X-138547)
- 3-(Benzyloxy)picolinonitrile (CAS 24059-90-3)
- Ephrin-A2-Selective YSA-Peptide (CAS 532441-10-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com