Levothyroxine Impurity 25 CAS CATO-C4X-167825

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-167825
Molecular FormulaC15H13ClI3NO4
Molecular Weight687.43 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Levothyroxine Impurity 25 CAS CATO-C4X-167825 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 687.43 g/mol gives Levothyroxine Impurity 25 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Levothyroxine Impurity 25 (CAS CATO-C4X-167825), a pharmacopoeial impurity reference standard (molecular formula C15H13ClI3NO4, MW 687.43 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Levothyroxine Impurity 25 (C15H13ClI3NO4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Levothyroxine Impurity 25 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC15H13ClI3NO4
Molecular Weight687.43 g/mol
Purity>95%
StorageStore at room temperature, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentCl/I-containing
Nitrogen Atoms1

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