Levothyroxine Impurity 41 CAS 2055-94-9

Description

The occurrence of Levothyroxine Impurity 41 is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, iodine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies Levothyroxine Impurity 41 (CAS 2055-94-9), a pharmacopoeial impurity reference standard (molecular formula C13H8I4O3, MW 719.82 g/mol) used for the identification and quantification of trace impurities in APIs.

Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, iodine substitution, an aromatic ring system, Levothyroxine Impurity 41 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 719.82 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO manufactures Levothyroxine Impurity 41 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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