Sorafenib Impurity 57 CAS 656-96-2
| CAS No. | 656-96-2 |
| Molecular Formula | C8H5ClF3NO |
| Molecular Weight | 223.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Sorafenib Impurity 57 (CAS 656-96-2), a certified reference material (molecular formula C8H5ClF3NO, MW 223.58 g/mol) for analytical method development and quality control.
Based on its molecular formula C8H5ClF3NO, Sorafenib Impurity 57 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 223.58 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Sorafenib Impurity 57 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5ClF3NO |
| Molecular Weight | 223.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Sorafenib Standards
- Sorafenib Impurity 32 (CAS 50528-86-4)
- Sorafenib Impurity 21 (CAS CATO-C4X-112421)
- Sorafenib Impurity 10 (CAS 2004659-85-0)
- Sorafenib Impurity 59 (CAS 284462-80-2)
- Sorafenib Impurity 30 (CAS 1012058-77-3)
- Sorafenib Impurity 45 (CAS 46843-47-4)
- Sorafenib Impurity 57 (CAS 99970-10-2)
- Sorafenib Impurity 12 (CAS 343247-69-8)
Recommended Standards
- N-Hydroxy-2-(trifluoromethoxy)benzene carboximidoyl chloride (CAS 74467-04-2)
- 2-Chloro-5-(trifluoromethyl)benzamide 20566-93-2 6957AD C8H5ClF3NO (CAS 20566-93-2)
- N-Formyl 2-chloro-5-trifluoromethylaniline (CAS 657-63-6)
- Benzaldehyde, 2-chloro-4-(trifluoromethyl)-, oxime (CAS 1188445-87-5)
- 2,2-Bis(ethylthio)-N-methylacetamide (CAS 240115-81-5)
- 3-(3-(3-Heptadecyl-5-thioxo-1H-1,2,4-triazol-4(5H)-yl)ureido)benzene-1-sulfonyl fluoride (CAS 23455-88-1)
- 2,3-Dihydro-1,4-ethanoquinoxaline-5-carbaldehyde (CAS 138023-46-8)
- 5-Fluoro-2-(2-piperidinyl)-1H-benzimidazole dihydrochloride (CAS 1185399-19-2)
- tert-Butyl 5-[amino(hydroxyimino)methyl]-6-methyl-3,4-dihydro[2,7]naphthyridine-2(1H)-carboxylate (CAS 1353519-45-5)
- 2-Chloro-5-(chloromethyl)-3-(difluoromethyl)-6-fluoropyridine (CAS 1806933-77-6)
- Diethyl 3-methoxybenzylphosphonate (CAS 60815-18-1)
- 4-[N-methyl-2-(2-methyl-1H-indol-3-yl)acetamido]butanoic acid (CAS 1099068-61-7)
- 4-Bromo-5-chloro-2-methoxyphenol (CAS 86735-03-7)
- Peptide Impurity 82 (CAS 10491-78-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com