Levothyroxine EP Impurity H CAS 2055-97-2
| CAS No. | 2055-97-2 |
| Molecular Formula | C13H6I4O4 |
| Molecular Weight | 733.80 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C13H6I4O4, Levothyroxine EP Impurity H contains a carboxylic acid group, a hydroxyl group, an ether linkage, iodine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 733.80 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Levothyroxine EP Impurity H (CAS 2055-97-2), a pharmacopoeial impurity reference standard (molecular formula C13H6I4O4, MW 733.80 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Levothyroxine EP Impurity H under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H6I4O4 |
| Molecular Weight | 733.80 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | I-containing |
Related Levothyroxine Standards
- Levothyroxine lmpurity 45 (CAS CATO-C4X-167845)
- Levothyroxine Impurity 26 (CAS 176258-88-1)
- Levothyroxine Impurity 20 (CAS 2230724-39-5)
- Levothyroxine Impurity 41 (CAS 2055-94-9)
- Levothyroxine EP Impurity D (CAS 67-30-1)
- Levothyroxine Impurity 44 (CAS 176258-89-2)
- Levothyroxine EP Impurity I (CAS 2016-06-0)
- Levothyroxine Related Compound (CAS 93647-48-4)
Recommended Standards
- N-[(1S)-1-[3',5'-Bis(1,1-dimethylethyl)[1,1'-biphenyl]-2-yl]-2-(diphenylphosphino)ethyl]-3,5-bis(trifluoromethyl)-benzamide (CAS 2089424-11-1)
- Methyl 4-((2S,3S)-3-((S)-2-((tert-butoxycarbonyl)(methyl)amino)propanamido)-8-cyano-5-((2-methoxynaphthalen-1-yl)methyl)-2-methyl-4-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepine-1-carbonyl)benzoate (CAS 2158322-16-6)
- Mal-amido-PEG9-NHS ester (CAS 2575631-92-2)
- N-Nitroso Amoxicillin Dimer Impurity 81 (CAS CATO-C4X-114881)
- Fosaprepitant Impurity 24 (CAS CATO-C4X-116824)
- Bromfenac Impurity 48 (CAS CATO-C4X-200248)
- Acotiamide Impurity 30 (CAS CATO-C4X-111430)
- 2-(3,5-Dichlorobenzyl)piperazine (CAS 907971-77-1)
- tert-Butyl 7-(aminomethyl)-6,7-dihydropyrazolo[1,5-a]pyrazine-5(4H)-carboxylate (CAS 1823417-79-3)
- 1-Cbz-pyrrolidine-2-carboxamide (CAS 93188-01-3)
- 0256AD 1185296-13-2 3-(3-Amino-propyl)-3H-benzooxazol-2-one hydrochloride C10H13ClN2O2 (CAS 1185296-13-2)
- 2',6'-Dimethoxy-[1,1'-biphenyl]-3-carbaldehyde (CAS 1242339-02-1)
- Lapatinib Impurity 43 (CAS CATO-C4X-119143)
- Neuropeptide Y (3-36) (porcine) trifluoroacetate salt (CAS 143863-88-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com